How Breast Cancer and Other Four Star-Rated Topics Relate to My DNA, Part 1

by Andrew Meyer on April 11, 2008

gene journalWhen you go into 23andMe’s Gene Journal, a place I’ve been frequenting a lot lately, you can view how diseases like Age-related Macular Degeneration apply to your own DNA.

Each disease, condition etc is given a research confidence rating from 1-4 stars. A topic with four star rating means that they are “widely accepted by the scientific community”.

23andme topic ratingTopics with lower ratings, 1-3 stars, means that they research “published in peer-reviewed journals but may not yet be widely accepted”.

Here is a list of topics given four stars by 23andMe (Only topics A-C):

1) Age-related Macular Degeneration
2) Alcohol Flush Reaction
3) Bitter Taste Perception
4) Blood Groups
5) Breast Cancer
6) Colorectal Cancer
7) Crohn’s Disease

Now here is how each of the above four star-topics apply to my own DNA:

Age-related Macular Degeneration

agmd

Can’t remember my family history of developing AMD in older age, so I will probably be doing some family sleuthing on the subject.

The above average odds calculation will probably make me more likely to pay more attention to general antioxidant vitamin and zinc intake and more willing to say “yes” to the eye exam people when they want to do extra things to my eyes.

Alcohol Flush Reaction

alcohol flush reaction

Bitter Taste Perception

bitter taste perception

Looks like I have an 80% chance of not being able to taste certain bitter flavors. This probably correlates to why I don’t put cream and sugar in my coffee when most of my friends load their coffees up.

coffee

My motto: The blacker and bolder the better.

Blood Groups

blood group1blood group2

All this one does it show me how limited my knowledge is of blood “types” and blood in general. Man, I will be spending plenty more time on this one later.

Breast Cancer

breast cancer

I know men can develop breast cancer, too, but not to worried about this higher than average odds calculation.

Colorectal Cancer

colorectal cancer

Anyone know how this is usually detected? I know how prostate cancer is checked for, but not colorectal cancer (see my earlier post on prostate cancer).

Oh yeah, know I remember. Colonoscopy!

colonoscopy

Crohn’s Disease

crohns disease

I will be covering more four star-topics (D-Z) in later posts.

If you would like me to share my genetic profile with you, go here. You can also view all our ‘My Genome’ posts here.

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  • Jeff
    Grandma Rudisaile has macular degeneration. I think Grandma Meyer did too.
  • For those that would want to test for colorectal cancer: Laboratory alternatives/additions to colonoscopy are available and new ones are emerging. You can test for blood in feces, do DNA-tests (http://www.nordiag.no/) or ELISA tests (http://www.phical.com/). I am sure there are more alternatives out there as well. Colonoscopy is probably still the safest bet, but this will hopefully change soon.
  • Sciphu, thanks for the heads-up on these other testing options. I'm going to enjoy watching how your blog-based publishing channel for the scientific community takes shape.
  • This is fascinating. I'll be looking forward to part 2
  • Thanks, Anne. It's coming.
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